Nov 15, 2023 | Diabetes Institute, Seminar, Symposium
Vendredi 1er décembre 2023 (Amphi Vulpian) 9h15-9h30 Welcome 9h30-9h40: presentation of the day… 9h40-11h00: Session 1: Newcomers 9h40-10h00: Benoit Viollet: Targeting AMPK and AMPK-related protein kinases to control blood glucose levels 10h00-10h20: Ralf Jockers: Why...
Nov 12, 2023 | Diabetes Institute, Functional Pharmacology and Pathophysiology of Membrane Receptors, Publications, Research
This study, from Ralf Jockers and Julie Dam’s team as part of a European network for the prevention of childhood obesity, OBELISK,defines impaired GLP1R cell surface expression as a risk factor for traits associated with type 2 diabetes and obesity and provides...
Nov 12, 2023 | Diabetes Institute, Functional pancreatic beta cell mass in rodent and human, Publications, Research, T-cell tolerance, biomarkers and therapies in type 1 diabetes
A collaborative work between the teams of R Mallone and R Scharfmann leaded by L Rachdi indicate that TRP could induce immune tolerance to β cells by promoting their immune evasion through HLA-I downregulation and PD-L1 upregulation.
Nov 12, 2023 | Diabetes Institute, Publications, Regulation of Glycemia by Central Nervous System, Research
Christophe Magnan and Céline Cruciani-Guglielmacci in collaboration with the team of Xavier Fioramonti highlight a new neuronal network involved in the regulation of the counter-regulatory response In particular, this study shows that DR 5-HT neurons detect...
Nov 12, 2023 | Immunity and Metabolism of Diabetes, Publications, Research
Here, we propose that a significant proportion of individuals may harbor an immune profile that renders them susceptible to developing T2D. We note the heterogeneity of circulating monocytes and tissue macrophages in organs that are key to metabolic disorders such as...
Oct 24, 2023 | Diabetes Institute, Immunity and Metabolism of Diabetes, Seminar
This event is organized by the Macrophage Club Îles-de-France (MCI), with support from the National Macrophage Club Community (MaCRO), with the goal of bringing together experts in France working on the biology of monocytes and macrophages.
Oct 17, 2023 | Diabetes Institute, Seminar
L’IHM du Diabète vous invite à sa demi-journée scientifique sur la thématique du « Dialogue inter-organes dans le diabète » le 4 Juillet 2023 de 9h à 13h, Amphithéâtre 3 Site Necker, 160 rue de Vaugirard, 75015 Paris Lien vers le formulaire d’inscription : ...
Jul 5, 2023 | Diabetes Institute, Publications, Regulation of Glycemia by Central Nervous System
Mireia Montaner, Jessica Denom, Wanqing Jiang, Christophe Magnan, Stefan Trapp, Hirac Gurden A. Schematic illustration of viral delivery in the OB and subsequent protocol performed to assess odor-induced CPIR in PPG-shRNA RD mice. Yellow circle represents peanut...
Jun 26, 2023 | Diabetes Institute, Publications
Marc Foretz, Bruno Guigas & Benoit Viollet Proposed mechanisms for metformin-induced reductions in blood levels of glucose. © Nature Reviews Endocrinology Abstract Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in most...
Jun 25, 2023 | Diabetes Institute, Seminar
L’IHM du Diabète vous invite à sa demi-journée scientifique sur la thématique du « Dialogue inter-organes dans le diabète » le 4 Juillet 2023 de 9h à 13h, Amphithéâtre 3 Site Necker, 160 rue de Vaugirard, 75015 Paris Lien vers le formulaire d’inscription : ...
